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CA2 — VTI1A
Text-mined interactions from Literome
Chen et al., Cell 1999
:
SNARE complex formation is
triggered by
Ca2+ and drives membrane fusion
Pang et al., J Neurosci 2006
:
Using knock-in mice that carry aspartate-to-asparagine substitutions in a Ca2+ binding site of synaptotagmin-1 ( the D232N or D238N substitutions ), we now show that the D232N mutation dramatically increases
Ca2+ dependent
SNARE complex binding by native synaptotagmin-1, but leaves phospholipid binding unchanged