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NFKB1 — RET
Text-mined interactions from Literome
Ludwig et al., Cancer Res 2001
(Carcinoma, Medullary...) :
RET induced
NF-kappaB and IKKbeta activity requires Ras function but does neither involve the classical mitogen activated protein kinase kinase/extracellular signal regulated kinase nor the phosphoinositide 3-kinase/Akt pathways ... In contrast,
RET induced
NF-kappaB activity is dependent on Raf and MEKK1
Ludwig et al., Oncogene 2003
:
Overexpression of Grap-2 inhibits
RET induced
NF-kappaB activation , and cotransfection of Grap-2 significantly reduces focus formation induced by oncogenic RET in NIH 3T3 cells
Gallel et al., Hum Pathol 2008
(Carcinoma, Medullary...) :
The results also support the hypothesis that
RET activation by somatic or germ line mutations may be
responsible for
NF-kappaB activation in MTCs