Katoh et al., Endocr Res 2002
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Overexpression of SIK repressed ACTH mediated expression of CYP11A- and Steroidogenic acute regulatory (StAR)-genes by inhibiting CREB bound to their promoters
Takemori et al., J Steroid Biochem Mol Biol 2003
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Salt-inducible kinase ( SIK ) , expressed in Y1 mouse adrenocortical tumor cells at an early stage of adrenocorticotropic hormone ( ACTH ) -stimulation, represses the cAMP-responsive element ( CRE ) -dependent gene expression of CYP11A and StAR by acting on bZIP domain of CRE binding protein