Tu et al., J Biol Chem 2006
:
IKK alpha regulates estrogen induced cell cycle progression by modulating E2F1 expression ... The role of IKKalpha in regulating E2F1 was not the result of reduced levels of cyclin D1, as overexpression of this gene could not overcome the effects of IKKalpha knock-down
Mussi et al., Mol Endocrinol 2006
:
Furthermore, overexpression of E2F1 significantly increases the promoter activity of the endogenous SRC-3 gene and boosts SRC-3 expression in vivo