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CDKN1A — USP22
Text-mined interactions from Literome
Atanassov et al., EMBO Rep 2011
(Cell Transformation, Neoplastic) :
Here, we show that
USP22 affects the expression of
p21 by altering far upstream element (FUSE) binding protein 1 ( FBP1 ) ubiquitination, as ablation of USP22 leads to increased FBP1 ubiquitination and decreased FBP1 protein occupancy at the p21 gene
Ling et al., Cell Mol Biol Incl Cyto Enzymol 2012
:
Collectively, Our findings indicate that USP22 may be responsible for HepG2 cell growth and
USP22 regulates the cell cycle via the c -- Myc/cyclin D2 pathway and down -- regulating p15 and
p21 expression in HepG2 cell