Gene interactions and pathways from curated databases and text-mining

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HMOX1 — KLF2

Text-mined interactions from Literome

Ali et al., Journal of thrombosis and haemostasis : JTH 2007 : We have identified a novel link between KLF2 and HO-1 in human vascular ECs, demonstrating that atorvastatin mediated HO-1 upregulation, and its associated antioxidant effect, is KLF2 dependent
Ali et al., J Biol Chem 2009 : Mechanistically, synergy required Akt phosphorylation, activation of Kruppel-like factor 2 , NF-E2 related factor-2 (Nrf2), increased nitric-oxide synthase activity, and enhanced HO-1 mRNA stability