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IL1RN — IL8

Text-mined interactions from Literome

Mo et al., Exp Eye Res 1999 (Uveitis) : The levels of LPS induced aqueous IL-8 and MCP-1 at 12 hr were inhibited by anti-TNFalpha mAb but not by an IL-1 receptor antagonist (IL-1Ra) , while concentrations of the two chemokines at 24 hr were inhibited by both anti-TNFalpha mAb and IL-1Ra
Mühlberg et al., J Clin Endocrinol Metab 2000 (Graves Disease) : Recent data have indicated that orbital fibroblasts ( OF ) can be stimulated to produce marked quantities of interleukin-1 receptor antagonist ( IL-1RA ), a powerful inhibitor of the proinflammatory activities of interleukin-1 in the orbital tissues in Graves ' ophthalmopathy ( GO )
Wolf et al., Clin Cancer Res 2001 (Carcinoma, Squamous Cell...) : HNSCCs were found to secrete and respond to functional IL-1alpha, in that culture supernatant from a high IL-1alpha secreting line, UM-SCC-11B, could induce secretion of cytokine IL-8 by a low IL-1alpha secreting line, UM-SCC-9 ; and the induction of IL-8 secretion could be blocked by the anti-IL-1alpha neutralizing antibody or the IL-1 receptor antagonist (IL-1RA)
Dongari-Bagtzoglou et al., Microb Pathog 2003 (Candidiasis, Oral) : To test whether IL-8 secretion is dependent on IL-1alpha activity, epithelial cells were challenged with viable C. albicans in the presence or absence of neutralizing anti-IL-1alpha antibody or IL-1ra , and IL-8 secretion was measured in the supernatants
Garat et al., Cytokine 2003 : The goal of this study was to determine the role of icIL-1Ra1 in regulation of cytokine induced IL-6 and IL-8 production in Caco-2 intestinal epithelial cells
Bertini et al., Cytokine 1992 : Recombinant icIL-1ra inhibited the IL-1 induced production of IL-6, IL-8 and monocyte chemotactic protein by human endothelial cells ( HEC )
Zoja et al., J Am Soc Nephrol 1992 : Recombinant interleukin-1 receptor antagonist blocked the interleukin-1 mRNA as well as interleukin-6 and interleukin-8 mRNA accumulation induced by interleukin-1 beta
Cominelli et al., Gastroenterology 1992 (Colitis) : Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitis
Kawano et al., Fertil Steril 2004 : The effects of IL-1alpha, IL-1 receptor antagonist (IL-1RA) , C2-ceramide, and C6-ceramide on the production of IL-6, IL-8 , and M-CSF by ESC
Lee et al., Infect Immun 2005 (Periodontitis) : The increased ICAM-1 and IL-8 expression in the THP-1 cells obtained with rMsps was not inhibited in the presence of the IL-1 receptor antagonist (IL-1ra) , a natural inhibitor of IL-1
Evans et al., Cytokine 2006 (Inflammation) : In addition, transfection of icIL-1ra1 in HeLa cells did not cause inhibition of IL-8 promoter activity following over-expression of the IL-1 signalling components MyD88, IRAK-1, TRAF-6, Ikappakappabeta or RelA
Kawano et al., Clin Exp Obstet Gynecol 2012 (MAP Kinase Signaling System) : The production of IL-8 was significantly increased by IL-1alpha or TNF-alpha, and the increase of IL-8 stimulated by IL-1alpha was suppressed by IL-1 ra in a dose dependent manner
Timper et al., Am J Physiol Endocrinol Metab 2013 (Insulin Resistance) : GIP induced mRNA expression of IL-6, IL-1ß, and the IL-1 receptor antagonist IL-1Ra , whereas TNFa, IL-8 , and monocyte chemotactic protein (MCP)-1 remained unchanged
Burger et al., J Clin Invest 1995 : The inhibitory activity of human interleukin-1 receptor antagonist is enhanced by type II interleukin-1 soluble receptor and hindered by type I interleukin-1 soluble receptor
Seitz et al., Eur J Immunol 1995 : In cells exposed to IL-1 beta, it also moderately stimulated IL-1ra production and release of soluble tumor necrosis factor receptor p75 ( sTNF-R p75 ) and inhibited IL-8 and MCP-1 production
Ruiz de Souza et al., Eur J Immunol 1995 : IVIg induced production of IL-8 by monocytes was enhanced by lipopolysaccharide (LPS), although LPS inhibited the secretion of IL-1ra , suggesting that IVIg and LPS stimulate distinct intracellular pathways in monocytes
Matsukawa et al., Lab Invest 1997 (Arthritis, Experimental...) : Maximum levels of TNF alpha and IL-8 were detected at 2 hours after LPS-injection, whereas IL-1 beta and IL-1 receptor antagonist (IL-1Ra) were detected at 6 and 9 hours, respectively ... These results provide new evidence that IL-8 as well as TNF alpha are the most proximal cytokines and induce subsequent production of IL-1 beta and IL-1Ra
Tesar et al., Blood Purif 1998 (Kidney Diseases...) : On the other hand, there was no change in serum levels of IL-1beta and IL-8 , and the serum levels of IL-1ra and IL-6 even increased at the end of a single PE, in spite of high levels of all cytokines and adhesion molecules in the plasma filtrate
Matsukawa et al., Lab Invest 1998 (Arthritis) : These results provide evidence that IL-8 and TNFalpha were responsible for the production of IL-1beta and IL-1Ra , and that IL-1beta was responsible for the second phase of IL-1beta and IL-8 production
Chen et al., Cancer Res 1998 (Carcinoma, Squamous Cell...) : We conclude that IL-1alpha can enhance the expression of cytokines IL-8 and GM-CSF in UM-SCC cell lines but that constitutive expression of these cytokines by UM-SCC is not inhibited by exogenous IL-1RA or neutralizing Ab