Gene interactions and pathways from curated databases and text-mining

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KLK3 — SLC2A4

Text-mined interactions from Literome

Liu et al., Mol Cell Biol 2002 : Moreover, the translocation of GLUT4 from intracellular vesicles to the plasma membrane was also inhibited by overexpression of the APS/Y ( 618 ) F mutant
Barrès et al., Mol Endocrinol 2006 (Diabetes Mellitus, Type 2...) : Expression of an APS mutant unable to bind Enigma increased the insulin induced Glut 4 translocation to the plasma membrane ... Taken together, these data strongly suggest that the interaction between APS and Enigma is involved in insulin induced Glut 4 translocation by regulating cortical actin remodeling and raise the possibility that modification of APS/Enigma ratio could participate in the alteration of insulin induced glucose uptake in adipose tissue