◀ Back to ARF6
ARF6 — CTBP2
Text-mined interactions from Literome
Paliwal et al., Mol Cell Biol 2006
(Colonic Neoplasms) :
Interaction with
ARF resulted in proteasome dependent
CtBP degradation ... Both
ARF induced CtBP degradation and
CtBP small interfering RNA led to p53 independent apoptosis in colon cancer cells ...
ARF induction of apoptosis was
dependent on its ability to interact with
CtBP , and reversal of ARF induced CtBP depletion by CtBP overexpression abrogated ARF induced apoptosis
Paliwal et al., Cancer Res 2007
(Lung Neoplasms) :
Furthermore, overexpression of
CtBP2 in ARF expressing cells enhanced cell migration, and an
ARF mutant defective in CtBP-family binding was
impaired in its ability to inhibit cell migration induced by CtBP2