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BAD — PIM1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: BAD → PIM1 (increases, BAD Activity) Kim et al., Br J Haematol 2006*
  Evidence: Upstream proteins known to phosphorylate BAD include Akt, extracellular signal-regulated kinase/mitogen-activated protein kinase (Erk/ MAPK), Pim-1 and Pim-2.

Text-mined interactions from Literome

Hu et al., Blood 2007 (Leukemia, Myeloid) : Induction of Pim1 protein by HOXA9 increases the phosphorylation and inactivation of the proapoptotic BAD protein, a target of Pim1
Gozgit et al., J Biol Chem 2008 : Decreased PIM1 mRNA corresponded with a decrease in Pim1 protein levels and inhibition of BAD phosphorylation at Ser ( 112 )