We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to EGFR

CXCR4 — EGFR

Text-mined interactions from Literome

Porcile et al., Ann N Y Acad Sci 2004 (Adenocarcinoma...) : CXCR4 activation induces epidermal growth factor receptor transactivation in an ovarian cancer cell line
Rahimi et al., Int J Cancer 2010 (Breast Neoplasms...) : EGFR variant mediated invasion by enhanced CXCR4 expression through transcriptional and post-translational mechanisms
Abhold et al., PloS one 2012 (Carcinoma, Squamous Cell...) : Activation of EGFR by the addition of EGF ligand or ectopic expression of EGFR in two established HNSCC cell lines ( UMSCC-22B and HN-1 ) resulted in the induction of CD44, BMI-1, Oct-4, NANOG, CXCR4 , and SDF-1
Zhao et al., PloS one 2012 (MAP Kinase Signaling System) : The inhibition of CXCL12 or CXCR4 by either neutralizing antibodies or small interfering RNA ( siRNA ) could completely block the CsA induced EGFR phosphorylation
Weekes et al., Neoplasia (New York, N.Y.) 2012 (Pancreatic Neoplasms) : Next, CXCR4 promoted intratumoral EGFR expression in association with temsirolimus resistance ... Next, CXCR4 promoted intratumoral EGFR expression in association with temsirolimus resistance