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EGF — IGFBP5
Text-mined interactions from Literome
Grimes et al., Endocrinology 1992
:
However, in the
presence of
epidermal growth factor ( which was without independent effect on the 30-kDa IGFBP ), insulin also induced this 30-kDa
IGFBP
Barreca et al., Mol Cell Endocrinol 1992
:
The
stimulation of IGF-I and
IGFBP secretion by
EGF appears to be dose dependent with a significant increment already evident at 5 nM
Nuttinck et al., Domest Anim Endocrinol 2004
:
Under defined culture conditions,
IGFBP-2 and FSHR mRNA expression remained at a high level in TCM199 alone and were significantly
reduced ( P < 0.05 ) in the presence of 10 ng/ml
EGF after a 24 h period of in vitro maturation
Mondschein et al., Endocrinology 1990
:
In contrast,
IGFBP-3 levels were
enhanced by
epidermal growth factor
Corps et al., Endocrinology 1991
:
Production of this
IGFBP by Swiss 3T3 cells was
stimulated by 50-150 % by the mitogens bombesin, vasopressin, platelet derived growth factor,
epidermal growth factor , and 12-O-tetradecanoylphorbol 13-acetate and also by IGF-I
Hana et al., Endocrinology 1994
(Endometrial Neoplasms) :
E2 had no significant effect on expression of any of the binding proteins, whereas
EGF increased
IGFBP-5 mRNA levels
Oguchi et al., Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi 1997
:
The
effects of IGF-I and
EGF on
IGFBP secretion diminished with increasing cell differentiation