Gene interactions and pathways from curated databases and text-mining

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CTD — STAT3

Text-mined interactions from Literome

Sagawa et al., Cancer Sci 2008 (Multiple Myeloma) : We further examined the effect of CTD on the IL-6 signaling pathway in myeloma cells, and found that CTD inhibited phosphorylation of STAT3 at tyrosine 705 residue as early as 1 h after treatment and down-regulated the expression of the antiapoptotic bcl-xL protein
Li et al., J Virol 2012 (Hepatitis C) : Further studies revealed that the C-terminal domain (CTD) of NS4B is sufficient for the activation of STAT3 , JNK, ERK, MMP-2, and Bcl-2