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CTD — STAT3
Text-mined interactions from Literome
Sagawa et al., Cancer Sci 2008
(Multiple Myeloma) :
We further examined the effect of CTD on the IL-6 signaling pathway in myeloma cells, and found that
CTD inhibited phosphorylation of
STAT3 at tyrosine 705 residue as early as 1 h after treatment and down-regulated the expression of the antiapoptotic bcl-xL protein
Li et al., J Virol 2012
(Hepatitis C) :
Further studies revealed that the
C-terminal domain (CTD) of NS4B is
sufficient for the activation of
STAT3 , JNK, ERK, MMP-2, and Bcl-2