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CYP11A1 — IGF1
Text-mined interactions from Literome
Huang et al., Biol Reprod 2001
:
Insulin-like growth factor-I alone had no effect on StAR or CYP17 mRNA expression but
increased LH receptor,
CYP11A , and 3beta-HSD mRNA levels
Lagaly et al., Mol Cell Endocrinol 2008
:
Adiponectin decreased ( P < 0.05 ) insulin induced progesterone and androstenedione production as well as attenuated
IGF-I induced LHR,
CYP11A1 , and CYP17A1 gene expression in theca cells. In contrast, adiponectin decreased ( P < 0.05 ) LHR mRNA abundance in granulosa cells but did not affect steroidogenic enzyme gene expression in granulosa cells. Adiponectin had no effect ( P > 0.10 ) on proliferation of large-follicle theca cells