Gene interactions and pathways from curated databases and text-mining

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PTGS2 — TRAF6

Text-mined interactions from Literome

Yeo et al., J Biol Chem 2003 : In contrast, overexpression of DN-IRAK1 or DN-TRAF6 only partially inhibited CpG DNA induced Cox-2 promoter activity and NF-kappaB activation, indicating the presence of additional signaling modulators downstream of MyD88
Lee et al., Eur J Pharmacol 2010 (MAP Kinase Signaling System) : Eupatolide inhibits lipopolysaccharide induced COX-2 and iNOS expression in RAW264.7 cells by inducing proteasomal degradation of TRAF6