Chen et al., Blood 2008
:
Furthermore, we found that Rap1b deficiency had no marked effect on LPS-, BCR-, or SDF-1 induced activation of mitogen activated protein kinases and AKT but clearly impaired SDF-1 mediated activation of Pyk-2 , a key regulator of SDF-1 mediated B-cell migration
Cipolla et al., Journal of thrombosis and haemostasis : JTH 2013
:
In fibrinogen-adherent platelets, both Pyk2 and PI3Kß were necessary for stimulation of the small GTPase Rap1b , a regulator of cell adhesion and spreading