◀ Back to MYC

MYC — OSM

Text-mined interactions from Literome

Kan et al., Cancer Res 2011 (Cell Transformation, Neoplastic) : Using isogenic human mammary epithelial cells ( HMEC ) at different stages of neoplastic transformation, we found that OSM signaling suppressed c-MYC expression and engaged a p16- and p53 independent growth arrest that required STAT3 activity
David et al., Am J Pathol 2012 (Bone Neoplasms...) : Knockdown experiments demonstrated that growth induction by OSM depends on both types I [leukemia inhibitory factor receptor ( LIFR ) ] and II [OSM receptor ( OSMR ) ] receptors, high STAT3 activation, and induction of MYC to a high expression level