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MAPK1 — MBP

Pathways - manually collected, often from reviews:

• WikiPathways MAPK Cascade: MAPK3/MAPK1 → MBP/MAP2/ELK1 (activation)
• WikiPathways Structural Pathway of Interleukin 1 (IL-1): MAPK3/MAPK1 → MBP (activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind_translation Interaction: MBP — MAPK1 (experimental interaction detection) Yang et al., J Biol Chem 1998*
• IRef Biogrid Interaction: MBP — MAPK1 (direct interaction, enzymatic study) Plun-Favreau et al., Nat Cell Biol 2007
• IRef Biogrid Interaction: MBP — MAPK1 (direct interaction, enzymatic study) Momose et al., J Immunol 2003*
• IRef Biogrid Interaction: MBP — MAPK1 (direct interaction, enzymatic study) Cavigelli et al., EMBO J 1995*
• IRef Biogrid Interaction: MBP — MAPK1 (direct interaction, enzymatic study) Tresini et al., Exp Cell Res 2001*
• IRef Biogrid Interaction: MBP — MAPK1 (physical association, affinity chromatography technology) Blaukat et al., Mol Cell Biol 2000*
• IRef Biogrid Interaction: MBP — MAPK1 (direct interaction, enzymatic study) Blaukat et al., Mol Cell Biol 2000*
• IRef Biogrid Interaction: MBP — MAPK1 (direct interaction, enzymatic study) Blaukat et al., FEBS Lett 1999*
• IRef Biogrid Interaction: MBP — MAPK1 (direct interaction, enzymatic study) Blaukat et al., Biol Chem 2001*
• IRef Intact Interaction: MBP — MAPK1 (phosphorylation reaction, protein kinase assay) Astigarraga et al., EMBO J 2007*

Text-mined interactions from Literome

Atkins et al., J Neurochem 1999 : Regulation of myelin basic protein phosphorylation by mitogen activated protein kinase during increased action potential firing in the hippocampus ... Here we investigated the physiological regulation of MBP phosphorylation by MAPK during neuronal activity in the alveus, the myelinated output fibers of the hippocampus
Galvin et al., J Neurosci Res 2010 : Pharmacological inhibition of MAPK signaling also prevented IGF-1 induced increases in myelin basic protein (MBP) , indicating that MAPK signaling was necessary to drive IGF-1 mediated enhancement of oligodendrocyte differentiation
Wendtner et al., Cancer Res 1995 (Hodgkin Disease) : Immune complex kinase assays showed that M44 mAb induced the activation of MAPK ( p42ERKII ) and the phosphorylation of a MAPK substrate, myelin basic protein
Hendrickson et al., Eur J Pharmacol 1998 : MAPK signaling was determined by assessing MEK ( also referred to as MAPK kinase ) activity by measuring phosphorylated extracellular signal regulated kinase ( pp44ERK - 1 and pp42ERK - 2 ) expression, and ERK activity by measuring ERK-2 dependent phosphorylation of myelin basic protein (MBP)