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ICAM1 — TIMP1

Text-mined interactions from Literome

Domeij et al., Biochem Biophys Res Commun 2005 (MAP Kinase Signaling System) : The results suggest that co-culture with monocytes enhances cellular expression of MMP-1 and TIMP-1 in gingival fibroblasts, and that the increased MMP-1 expression, in contrast to TIMP-1, is partly mediated by the adhesion molecule ICAM-1 and the p38 MAPK signal pathway
Zhang et al., J Gerontol A Biol Sci Med Sci 2006 (Albuminuria...) : As several inflammatory mediators including intercellular adhesion molecule-1 ( ICAM-1 ) are substrates of MMPs, we speculated that TIMP-1 might affect ICAM-1 through MMPs and subsequently promote age related renal fibrosis ... It was found that the expressions and activities of gelatinases were downregulated ; the expressions of ICAM-1 , collagen III, collagen IV, and transforming growth factor (TGF)-beta1 were upregulated ; and the number of infiltrating macrophages was increased in kidneys of 24-month-old TIMP-1 transgenic mice with high expressions of TIMP-1 , compared with wild-type mice