Gene interactions and pathways from curated databases and text-mining

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CA2 — LEP

Text-mined interactions from Literome

Alver et al., J Enzyme Inhib Med Chem 2004 : The effect of carbonic anhydrase inhibition on leptin secretion by rat adipose tissue
Glavaski-Joksimovic et al., Neuroendocrinology 2004 : The ability of leptin to induce an increase in intracellular Ca2+ concentration ([Ca2+]i) in somatotropes was examined in dispersed porcine pituitary cells using a calcium imaging system ... Leptin increased [Ca2+ ] i in porcine somatotropes in a dose dependent manner
Scanes et al., Neuroendocrinology 2007 : Similarly, [ Ca2+ ] i was increased by perifusion with pituitary adenylate cyclase activating peptide in 85 % and by leptin but only in 51 % of somatotropes
Avelino-Cruz et al., Mol Cell Endocrinol 2009 : Leptin increases L-type Ca2+ channel expression and GnRH stimulated LH release in LbetaT2 gonadotropes