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Cartee et al., Cancer Res 2001
:
In U937 cells, coadministration of FP blocked PMA induced expression and reporter activity of the CDKI p21WAF/CIP1 and triggered caspase mediated cleavage of the CDKI p27KIP1 Rosato et al., Mol Cancer Ther 2002
(Leukemia) :
FP also blocked SB-related p21WAF1-CIP1 induction through a caspase independent mechanism and triggered the caspase mediated cleavage of p27KIP1 and retinoblastoma protein