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IL3 — PARP1

Text-mined interactions from Literome

Arai et al., J Biol Chem 2001 : Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin mediated hematopoietic cell adhesion ... These results suggest that Epo and IL-3 activate Rap1 at least partly through the CrkL-C3G complex as well as through additional pathways most likely involving phospholipase Cgamma and strongly implicate Rap1 in regulation of beta ( 1 ) integrin mediated hematopoietic cell adhesion
Epperly et al., Exp Hematol 2003 : The cell lines overexpressing MnSOD ( 1F2 or 2C6 ) displayed decreased radiation induced, TNF-alpha induced, or IL-3 withdrawal induced mitochondrial membrane permeability, caspase-3 and PARP activation, and apoptosis