◀ Back to IL10
CD8B — IL10
Text-mined interactions from Literome
Tscharke et al., Arch Virol 1999
(Disease Models, Animal...) :
The determine which cytokines might be involved in the
CD8 ( + ) cell dependent
response to ganglionic HSV infection, IL-2, IL-4, IL-6,
IL-10 , and IFN-gamma mRNA levels were measured in infected ganglia from immunocompetent and anti-CD8 treated mice
John et al., Infect Immun 2000
:
Depletion of
CD8 ( + ) cells from PBMC decreased IFN-gamma but
increased IL-10 production ...
CD8 ( + ) T cells are the major source of IFN-gamma but may
suppress production or secretion of
IL-10
Nakamura et al., J Immunol 2003
:
The generation of the efferent
CD8 ( + ) Tr cell in a.c. associated immune deviation is
dependent on
IL-10 producing, CD1d restricted, invariant Valpha14 ( + ) NKT ( iNKT ) cells
Horwitz et al., J Leukoc Biol 2003
:
The
role of the combination of IL-2 and TGF-beta or
IL-10 in the generation and function of CD4+ CD25+ and
CD8+ regulatory T cell subsets
Liu et al., J Immunol 2003
:
IL-10 mediates suppression of the
CD8 T cell IFN-gamma response to a novel viral epitope in a primed host
Dercamp et al., Cancer Res 2005
(Thymoma) :
Distinct and overlapping
roles of
interleukin-10 and CD25+ regulatory T cells in the inhibition of antitumor
CD8 T-cell responses ... Here, we address some of the respective and possibly overlapping
roles of
IL-10 and CD25+ T ( reg ) in
CD8 antitumor immunity
Willemsen et al., J Immunol 2006
(Melanoma) :
The introduction of a mutated cysteine motif in CD8alpha, which prevents its binding to LCK and linker for activation of T cells, did not adversely affect expression and T cell cytotoxicity, but counteracted the
CD8alpha mediated down-regulation of IL-4 and IL-5, but not
IL-10
Murugaiyan et al., J Immunol 2007
(Neoplasms) :
Lower levels of CD40L expression on T cells induced
IL-10 mediated suppression of tumor regressing effector
CD8 ( + ) T cells and higher productions of IL-4 and IL-10
Ismail et al., Infect Immun 2007
(Disease Models, Animal...) :
Depletion of
IL-10 restored the number of CD4 ( + ) and
CD8 ( + ) T cells in infected WT mice
Saha et al., J Immunol 2007
(Disease Susceptibility...) :
Both CD4 ( + ) and
CD8 ( + ) T cells were
involved in IFN-gamma and
IL-10 production
Björck et al., J Immunol 2008
:
IC-loaded pDC stimulate CD4 ( + ) T cells to proliferate and secrete a mixture of IL-4 and IFN-gamma, and they
induce CD8 ( + ) T cells to secrete
IL-10 as well as IFN-gamma
Chaput et al., Gut 2009
(Adenocarcinoma...) :
Finally,
interleukin 6 and TGF beta 1 synergistically
induced the generation of
CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo
Parvizi et al., Vet Immunol Immunopathol 2009
(Marek Disease) :
Our results indicate that cytokines could be differentially induced by MDV in CD4 ( + ) and
CD8 ( + ) T cell subsets and that
IL-10 may
play a role in the modulation of immune response to MDV
Ma et al., Scand J Immunol 2011
(Colonic Neoplasms) :
This study aims to investigate the
role of tumour derived Foxhead box P3 (Foxp3) ( +
) interleukin (IL)-17 ( + ) T cells on suppressing tumour-specific
CD8 ( + ) T cells
Brisbin et al., Benef Microbes 2012
:
The results demonstrated that chicken CD4+ and
CD8+ T-cells express TLR21 and that the various isolates of lactobacilli differentially
induces the expression of
interleukin 10 , interferon-gamma and transforming growth factor beta
Höllsberg et al., Proc Natl Acad Sci U S A 1995
:
CD8 T-cell stimulation with the wild-type peptide antigen
led to activation of p56lck kinase activity,
interleukin 2 secretion, cytotoxicity, and clonal expansion
Barth et al., Ann Surg Oncol 1996
(Sarcoma, Experimental) :
In an in vitro assay,
IL-10 did not
inhibit CD8 lymphocyte secretion of IFN-gamma in response to tumor stimulation