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IL10 — SLAMF1

Text-mined interactions from Literome

Meroni et al., Clin Immunol 1999 (HIV Infections) : Results showed that : ( 1 ) SLAM expressing CD4 ( + ) and CD8 ( + ) lymphocytes diminish in group A patients compared to both group B patients and HC ; ( 2 ) SLAM expression on CD4 ( + ) lymphocytes is preferentially associated with the lack of CD7 on cell surface ( CD4 ( + ) CD7 ( - ) produce IL-10 but not IFN-gamma ) ; ( 3 ) SLAM engagement increases HIV env peptide stimulated, but neither tetanus toxoid- nor PHA stimulated proliferation of peripheral blood mononuclear cells ( PBMC ) in patients but not in HC ; and ( 4 ) SLAM engagement augments IFN-gamma and reduces IL-10 production by env peptide stimulated PBMC of HIV infected individuals
Isomäki et al., J Immunol 1997 (Arthritis, Rheumatoid) : Interestingly, SLAM expression on activated CD4+ and CD8+ T cells from both patients and healthy individuals could be down-regulated by IL-10 , which has been previously shown to function as an anti-inflammatory molecule in rheumatoid synovium