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PAK1 — RNF19A
Text-mined interactions from Literome
Lee et al., J Biol Chem 2001
:
This betaPix induced
p38 activation was
blocked by coexpression of dominant negative Cdc42/Rac or kinase-inactive
PAK , indicating that the effect of betaPix on p38 is exerted through the Cdc42/Rac-PAK pathway and requires PAK kinase activity
Dechert et al., Am J Physiol Cell Physiol 2001
(MAP Kinase Signaling System) :
Phosphorylation of p38 mitogen activated protein kinase ( MAPK ) in cells overexpressing wild-type PAK1 was similar to vector controls ; however,
p38 MAPK phosphorylation was severely
reduced by overexpression of the
PAK1 mutant
Chan et al., J Biol Chem 2008
(MAP Kinase Signaling System) :
Inhibition of MAPK pathways showed that MEK-ERK signaling but not
p38 is
required for full
PAK activation and focal adhesion turnover
Huang et al., Mol Cell Biol 1998
:
These data indicate that separate signals are required for activation and inactivation of Paks and that, in contrast to other cell types, activated
Pak does not
trigger activation of JNK or
p38-MAPK in neutrophils