◀ Back to IL22
IL17D — IL22
Text-mined interactions from Literome
Shen et al., Scand J Rheumatol 2013
(Behcet Syndrome...) :
Elevated levels of
interleukin-27 and
effect on production of interferon-? and
interleukin-17 in patients with Behçet 's disease
Wang et al., Immunol Lett 2013
:
In the present study, we demonstrate that
IL-27 inhibits the production of
IL-22 and induces the expression of IFN-? in CD4 ( + ) T cells from human umbilical cord blood mononuclear cells ( CBMCs ) stimulated with anti-CD3 and anti-CD28 in dose dependent manner ... Moreover,
IL-27 inhibits the production of
IL-22 in CD4 ( + ) CD45RA ( + ) and CD4 ( + ) CD45RO ( + ) T cells from PBMCs ... These data identify that
IL-27 may
suppress the production of
IL-22 by inducing the expression of SOCS1 in human CD4 ( + ) T cells