Gene interactions and pathways from curated databases and text-mining

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MMP2 — PTEN

Text-mined interactions from Literome

Zhang et al., J Biol Chem 2004 (Carcinoma, Lewis Lung) : MMP-2 induction was blocked by the PI 3-kinase inhibitors LY294002 and wortmannin, by overexpression of a dominant negative Akt or wild-type PTEN ( phosphatase and tensin homologue deleted on chromosome 10 ), and by rapamycin
Furukawa et al., Int J Oncol 2006 (Brain Neoplasms...) : Ad5CMV-PTEN transfer into the glioma cell lines lacking the wild-type gene product decreased the levels of matrix metalloproteinase (MMP)-2 mRNA and inhibited the enzymatic activities of MMP-2 and MMP-9
Tian et al., Oncol Rep 2010 (Carcinoma, Hepatocellular...) : On the molecular level, overexpression of PTEN suppressed expression of matrix metalloproteinase (MMP)-2 and -9 in HepG2 cells
Chen et al., Nan Fang Yi Ke Da Xue Xue Bao 2013 : MMP-2/MMP-9 inhibitor III did not obviously affected the expression of PTEN , VEGF or Flk-1 as compared with the non transfected or empty vector transfected cells