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JAK2 — PTPRC
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Zhou et al., J Immunol 2003
:
This study indicates that the
JAK phosphatase activity of CD45 can be
induced by
anti-CD45 Ab treatment, and this principle may find clinical application in modulation of JAK activation in immune mediated diseases
Wu et al., Mol Immunol 2009
(MAP Kinase Signaling System) :
CD45 recruits adapter protein DOK-1 and negatively
regulates JAK-STAT signaling in hematopoietic cells
Lo et al., Blood 2012
(Cell Transformation, Neoplastic...) :
CD45 , a protein tyrosine phosphatase and a negative
regulator of cytokine/growth factor receptor and
JAK/STAT signaling, is among those targets