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COL4A2 — MMP9
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Ahmed et al., J Cell Biochem 2002
(Ovarian Neoplasms) :
Plasminogen dependent [ 3H ]
-collagen IV degradation was
inhibited by inhibitor of uPA ( amiloride ) and
MMP ( phenanthroline ) and by antibodies against uPA or MMP-9 or alphavbeta6 integrin, indicating the involvement of alphavbeta6 integrin, uPA and MMP-9 in the process
Davis et al., Neurol Res 2007
(Brain Edema...) :
The ex vivo study also revealed that
matrix metalloproteinase (MMP)-9 plays a key role in exercise strengthened
collagen IV expression against ischemia/reperfusion injury
Altincicek et al., Dev Comp Immunol 2008
:
Recently, we postulated that an endogenous
MMP expressed in the lepidopteran model Galleria mellonella during metamorphosis
causes degradation of
collagen-IV , which in turn results in activation of innate immunity
Guo et al., Neuroscience 2008
(Brain Edema...) :
The ex vivo study also revealed a key
role of
MMP-9 in exercise strengthened
collagen IV expression against I/R injury
Takamiya et al., J Neurosci Res 2011
(Brain Ischemia...) :
Treatment with nPts greatly reduced this decrease of
collagen IV and
activation of
MMP-9 and, with large reductions of MMP-9 activation on zymography and superoxide production
Schäfer et al., BMC cancer 2012
(Neovascularization, Pathologic...) :
Taken together, these results indicate that a GLV-1h255 mediated intra-tumoral over-expression of
MMP-9 leads to a degradation of
collagen IV , facilitating intra-tumoral viral dissemination, and resulting in accelerated tumor regression
Yu et al., Genes Dev 1999
(Mammary Neoplasms, Experimental...) :
CD44 associated cell surface
MMP-9 promotes cell mediated
collagen IV degradation in vitro and mediates tumor cell invasion of G8 myoblast monolayers