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CPT2 — LEP
Text-mined interactions from Literome
Yamagishi et al., J Biol Chem 2001
:
Leptin induced ROS generation,
CPT-1 activation , ACC inhibition, and MCP-1 overproduction were found to be completely prevented by either genistein, a tyrosine kinase inhibitor, H-89, a protein kinase A (PKA) inhibitor, or tetradecylglycidate, a CPT-1 inhibitor
Luo et al., Mol Cell Biochem 2008
:
Furthermore, at the level of 10 and 100 ng/ml
leptin not only selectively
increased the gene expression of PGC-1alpha,
CPT1 , Cyt c, UCP2, and UCP3 ( P < 0.05 ), but also enhanced COX enzyme activity which related to mitochondrial FAO