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EGF — GRK6

Text-mined interactions from Literome

Gao et al., FEBS Lett 2005 : Immunoprecipitation experiments showed that EGF stimulation increased GRK2 binding to EGFR complex in HEK293 cells coexpressing EGFR and GRK2 ... The EGF induced GRK2-EGFR complex formation was greatly reduced by perturbation of EGFR and Src tyrosine kinase activity ... Furthermore, studies with GRK2 mutants showed that neither catalytic activity nor the N-terminal domain of GRK2 was required for EGF induced GRK2-EGFR complex formation
Gao et al., Acta Biochim Biophys Sin (Shanghai) 2005 (MAP Kinase Signaling System) : Immunoprecipitation and immunofluorescence experiments show that EGF stimulates GRK2 binding to EGFR complex and GRK2 translocating from cytoplasm to the plasma membrane in human embryonic kidney 293 cells