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VPS29 — VPS35

Pathways - manually collected, often from reviews:

• Reactome Reaction: VPS29 → VPS35 (direct_complex)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: VPS35 — VPS29 (colocalization, biochemical) Havugimana et al., Cell 2012
• IRef Biogrid Interaction: VPS35 — VPS29 (physical association, affinity chromatography technology) Kristensen et al., Nat Methods 2012
• MIPS CORUM Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A): Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) complex (SNX1-SNX2-VPS26A-VPS29-VPS35) Haft et al., Mol Biol Cell 2000
• MIPS CORUM Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26B): Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26B) complex (SNX1-SNX2-VPS26B-VPS29-VPS35) Haft et al., Mol Biol Cell 2000
• MIPS CORUM VPS35-VPS29-VPS26A complex: VPS35-VPS29-VPS26A complex complex (VPS26A-VPS29-VPS35) Haft et al., Mol Biol Cell 2000
• MIPS CORUM Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A): Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) complex (SNX1-SNX2-VPS26A-VPS29-VPS35) Shi et al., Nature structural & molecular biology 2006*
• IRef Corum Interaction: Complex of 26 proteins (association, two hybrid) Haft et al., Mol Biol Cell 2000
• IRef Corum Interaction: Complex of 11 proteins (association, far western blotting) Haft et al., Mol Biol Cell 2000
• IRef Dip Interaction: VPS35 — VPS29 (direct interaction, molecular sieving) Hierro et al., Nature 2007*
• IRef Dip Interaction: VPS35 — VPS29 (direct interaction, anti tag coimmunoprecipitation) Hierro et al., Nature 2007*
• IRef Dip Interaction: VPS35 — VPS29 (direct interaction, x-ray crystallography) Hierro et al., Nature 2007*
• IRef Dip Interaction: Complex of 16 proteins (physical association, molecular sieving) Hierro et al., Nature 2007*
• IRef Hprd Interaction: VPS35 — VPS29 (two hybrid) Haft et al., Mol Biol Cell 2000
• IRef Hprd Interaction: VPS35 — VPS29 (in vitro) Haft et al., Mol Biol Cell 2000
• IRef Ophid Interaction: VPS35 — VPS29 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Restrepo et al., Traffic 2007 : Interestingly, Vps35-R ( 98 ) W expression destabilized Vps26p while having no effect on Vps29p stability, while Vps35-Q ( 733 ) * expression affected Vps29p stability but had no effect on Vps26p
Zelazny et al., J Biol Chem 2013 : Then, by combining live-cell imaging with immunochemical and genetic approaches, we report that VPS35 alone is able to bind to endosomal membranes and plays an essential role in VPS26 and VPS29 membrane recruitment