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HAVCR2 — TNF
Text-mined interactions from Literome
Hastings et al., Eur J Immunol 2009
:
In addition, human CD4 ( + ) T cells secreted elevated levels of IFN-gamma, IL-17, IL-2, and IL-6, but not IL-10, IL-4, or
TNF-alpha , when stimulated with anti-CD3/anti-CD28 in the
presence of
TIM-3-specific , putative antagonistic antibodies
Qiu et al., PLoS Pathog 2012
(Tuberculosis) :
Mechanistic experiments showed that siRNA silencing of
Tim-3 or soluble Tim-3 treatment interfering with membrane Tim-3-ligand interaction
reduced de novo production of IFN-? and
TNF-a by Tim-3 expressing T cells