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IL2RB — TNF
Text-mined interactions from Literome
Glosli et al., Eur J Haematol 1999
:
Human
TNFalpha binds to and
activates the murine p55 receptor, but not the
p75 receptor
Shaw et al., J Pharmacol Exp Ther 2009
:
In summary,
TNFalpha acts through p55 and
p75 receptors to precipitate an innocuous inflammatory cascade
Lee et al., Biochem Biophys Res Commun 2009
:
TNF-alpha augmented the IL-15 induced expression of NK1.1 and
CD122 in mature NK cells, and TNF-alpha alone also induced NK cell maturation as well as IL-15
Muñoz-Fernández et al., Eur J Immunol 1990
:
More interestingly,
TNF significantly
increased the number of high-affinity
IL2R on purified T cells in the presence of phorbol 12,13-dibutyrate
Panzer et al., Clin Exp Immunol 1993
:
We show in this system that exogenously added IL-1 beta, IL-6 and
TNF-alpha induces
IL-2 receptor (R) up-regulation and IL-2 production, and proliferation by both CD4+ and CD8+ cells
Boone et al., FEBS Lett 1998
(Fibrosarcoma) :
TNF signaling can be
mediated by p55 or
p75 TNF receptors