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CD40 — CTLA4

Text-mined interactions from Literome

Pioli et al., J Immunol 2000 : Our results show that CD40 or LPS stimulation in the presence of IL-4 induces CTLA-4 expression in purified B cells ; the maximum level is reached in both membrane and intracellular compartments after 48-72 h. Engagement of the B cell CTLA-4 by immobilized mAb inhibits IgG1 and IgE production and reduces the frequency of IgG1- and IgE expressing B cells
Fallarino et al., J Immunol 2002 : Remarkably, the activation of CD40 on DCs under conditions that would increase Th1 cell proliferation, also resulted in down-regulation of surface CTLA-4
Ding et al., Shock 2004 (Sepsis) : In peritoneal cells, the expression of CD40 , CD80, and CD86 was unchanged, but their respective ligands CD40L, CD28, and CD152 all increased in mice 24 h after CLP, although no such change was observed in splenocytes