Gene interactions and pathways from curated databases and text-mining

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CD40 — VCAM1

Text-mined interactions from Literome

Jollow et al., Transplantation 1999 : CD40-CD40L interactions induced the expression of the adhesion molecules VCAM-1 and E-selectin and the costimulatory molecule CD80 but not CD86 ( B7-2 ) on the MECs
Propst et al., J Immunol 2000 (Inflammation) : Cross linking epithelial CD40 had no effect on expression of the adhesion molecule VCAM-1
Rushworth et al., Transplantation 2002 : We have previously shown that binding of human CD154 expressed on the Jurkat D1.1 cell line to porcine CD40 on pig aortic endothelial cells ( PAECs ) can lead to up-regulation of vascular cell adhesion molecule (VCAM)-1 and MHC class II
Longo et al., Circulation 2003 : In human coronary artery ECs ( HCAECs ), adenovirus mediated overexpression of A20 blocks physiological, CD40 induced activation of NF-kappaB, upstream of IkappaBalpha degradation ( Western blot ) and subsequently upregulation of ICAM-1, VCAM-1 , and E-selectin ( flow cytometry )
Yellin et al., J Leukoc Biol 1995 (Arthritis, Rheumatoid...) : Ligation of CD40 on fibroblasts induces CD54 ( ICAM-1 ) and CD106 ( VCAM-1 ) up-regulation and IL-6 production and proliferation ... CD40 expression on fibroblasts is functionally significant because CD40L-CD40 interactions induce SM fibroblast CD54 ( intercellular adhesion molecule-1 ) and CD106 ( vascular cell adhesion molecule-1 ) up-regulation
Karmann et al., J Exp Med 1996 : We have reported previously that activation of human umbilical vein endothelial cells ( HUVECs ) through CD40 , using a recombinant soluble form of trimerized CD40 ligand, leads to induction of E-selectin, vascular cell adhesion molecule-1 ( VCAM-1 ), and intercellular adhesion molecule-1 ( ICAM-1 )