Gene interactions and pathways from curated databases and text-mining

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PPARGC1A — SP1

Pathways - manually collected, often from reviews:

  • BioCarta mechanism of gene regulation by peroxisome proliferators via ppara: PPAR-alpha/Transcription factors complex (PPARA-JUN_RELA_SP1) → PPAR-alpha/PPAR ligands/RXR/Co-Activators complex (PPARA-RXRA-CITED2_NCOA1_PPARGC1A_CREBBP_NRIP1_EP300_PPARBP_SRA1) (transcription, inhibits)
  • FastForward regulation: SP1 → PPARGC1A (transcriptional regulation, unknown)
    Evidence: DNABINDING