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ATM — CYP19A1

Text-mined interactions from Literome

a Marca Pereira et al., Aquat Toxicol 2011 : Exposure of ovary explants to 100 ng/mL 1,4,6-androstatriene-3,17-dione (ATD) , a potent pharmaceutical aromatase inhibitor , reduced E2 concentrations and elevated T concentrations confirming that CYP19 activity could be inhibited in the assay
Zhang et al., Neurochem Res 2012 (Pain) : Inhibition of local E2 synthesis by 1,4,6-Androstatrien-3,17-dione ( ATD , a potent irreversible aromatase inhibitor ), or blockade of ERs by ICI 182,780 produced an inhibitory effect on the late phase of formalin nociceptive responses
Slama et al., Exp Brain Res 1986 (Prenatal Exposure Delayed Effects) : The fact that, under our in vitro experimental conditions, ATD is able to displace testosterone binding in the hypothalamus whereas estradiol does not, confirms the hypothesis that ATD acts on aromatase