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FGF21 — IRS1
Text-mined interactions from Literome
Lassarre et al., Endocrinology 2003
(Breast Neoplasms) :
They further suggest that the
FGF induced increase in
IRS-1 counterbalances the inhibition of IRS-1 tyrosine phosphorylation to allow normal stimulation of IGF-I induced PI 3-kinase activity
Li et al., Mol Cell Endocrinol 2012
:
In 3T3-L1 adipocytes, the up-regulation of
FGF-21markedly increased GUR, decreased intracellular triglyceride ( TG ) content, up-regulated ß-klotho, FGFR1, GLUT-1,
IRS-1 , ATGL, HSL, and ap2 mRNA expressions ( p < 0.05 )