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CXCR4 — EGF
Text-mined interactions from Literome
Porcile et al., Exp Cell Res 2005
(Carcinoma...) :
Our results further indicate that
CXCR4 activation
induces EGF receptor (EGFR) phosphorylation that in turn was linked to the downstream intracellular kinases activation, ERK1/2 and Akt
Guo et al., Colloids Surf B Biointerfaces 2007
(Neoplasm Metastasis...) :
In this research, the result first showed that
epidermis growth factor (EGF) enhanced the expression of
CXCR4 and the migration of ovarian cancer cells, moreover, both stromal cell derived factor-1alpha ( SDF-1alpha ) and EGF induced high matrix metallopeptidase 9 (MMP9) expressions
Prasad et al., Int J Oncol 2009
(Breast Neoplasms) :
These results demonstrate a positive role of SHIP2 in
EGF induced Akt activation,
CXCR4 expression, and cell migration in breast cancer cells ... These results demonstrate a positive role of SHIP2 in
EGF induced Akt activation,
CXCR4 expression, and cell migration in breast cancer cells
Al Zobair et al., Oncol Rep 2013
(Carcinoma, Non-Small-Cell Lung...) :
Furthermore, we showed that
EGF enhanced the expression of
CXCR4 in NSCLC cells through the PI-3K pathway, and treatment of NSCLC cells with EGFR phosphorylation inhibitor, AG1478, resulted in downregulation of the expression of CXCR4