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EDAR — NFKB1

Text-mined interactions from Literome

Koppinen et al., Exp Cell Res 2001 : When Edar was expressed at low levels, the NF-kappaB response was enhanced by coexpression of ectodysplasin
Shindo et al., Biochem Biophys Res Commun 2004 (Ectodermal Dysplasia) : While IKK1/IKKalpha and IKK2/IKKbeta are required for EDAR induced NF-kappaB activation, they are dispensable for its ability to repress Lef-1/beta-catenin dependent transcription ... In contrast, NIK is not involved in EDAR induced NF-kappaB activation or Lef-1/beta-catenin transcriptional repression
Morlon et al., Hum Mol Genet 2005 (Ectodermal Dysplasia) : TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd
Chassaing et al., Br J Dermatol 2010 (Ectodermal Dysplasia...) : EDARADD interacts with the TAB2/TRAF6/TAK1 complex, which is necessary for NF-kappaB activation by EDAR