Germani et al., Oncogene 2003
:
Our results suggest that p21 ( Waf-1/Cip-1 ) induction by SIAH-1 could not be mediated by CtIP degradation
Chinnadurai et al., Biochim Biophys Acta 2006
(Cell Transformation, Neoplastic...) :
Depletion of Ctip in established mouse embryo fibroblasts arrests cells in G1 and results in an accumulation of hypophosphorylated Rb and the Cdk inhibitor p21 , suggesting that CtIP is also a critical regulator of G1/S transition of the cell cycle
Cherrier et al., Oncogene 2009
:
In addition, CTIP2 and SUV39H1 were recruited to the silenced p21 gene promoter to cooperatively inhibit p21 gene transcription