Gene interactions and pathways from curated databases and text-mining

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CCL20 — HNRNPH1

Text-mined interactions from Literome

Fushimi et al., J Clin Invest 2000 (Neoplasms, Experimental) : Since the human CC chemokine, macrophage inflammatory protein 3alpha ( MIP-3alpha ), is chemotactic for DCs in vitro, we hypothesized that adenovirus mediated gene transfer of MIP-3alpha ( AdMIP-3alpha ) to tumors might induce local accumulation of DCs and inhibit growth of preexisting tumors
Le Borgne et al., Immunity 2006 : Recruitment of circulating DC precursors, including Gr1+ monocytes, precedes the sequential accumulation of CD11c+ MHC class II+ DCs in dermis and epithelium via a CCR6/CCL20 dependent mechanism
Biragyn et al., J Immunol 2007 (Lymphoma, B-Cell) : Although the Ag targeting alone, without activation of dendritic cells (DCs), is proposed to induce tolerance, and MIP3alpha does not directly activate DCs , the MIP3alpha based vaccine efficiently induced protective and therapeutic antitumor responses
Dieu et al., J Exp Med 1998 : Finally, detection by in situ hybridization of MIP-3alpha mRNA only within inflamed epithelial crypts of tonsils, and of MIP-3beta mRNA specifically in T cell-rich areas, suggests a role for MIP-3alpha/CCR6 in recruitment of immature DCs at site of injury and for MIP-3beta/CCR7 in accumulation of antigen loaded mature DCs in T cell-rich areas