Gene interactions and pathways from curated databases and text-mining

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B2M — CD4

Text-mined interactions from Literome

Franco et al., Eur J Clin Microbiol Infect Dis 1999 (Acquired Immunodeficiency Syndrome) : After starting therapy, the mean HIV-1 RNA serum levels decreased and the mean CD4 + cell counts increased from baseline to week 36 ( P < 0.001 ). Mean levels of tumor necrosis factor alpha receptor type II, tumor necrosis factor alpha and beta2-microglobulin as well as expression of human leukocyte antigen-DR were significantly reduced at the end of follow-up ( P < 0.01 ). Deactivation kinetics of these parameters was similar in patients with CD4+ counts > 200 cells/microl at baseline versus those with CD4 + counts < 200 cells/microl at baseline, despite higher activation at baseline in the group with < 200 cells/microl
Naji et al., Blood 2007 : CD3+CD4low and CD3+CD8low are induced by HLA-G : novel human peripheral blood suppressor T-cell subsets involved in transplant acceptance ... In addition, these HLA-G induced CD3 ( + ) CD4 ( low ) and CD3 ( + ) CD8 ( low ) subpopulations are Foxp3 negative suppressor T cells whose function involves IL-10