Gene interactions and pathways from curated databases and text-mining

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INPP5D — LYN

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: INPP5D → LYN (directlyIncreases, INPP5D Activity)
    Evidence: SHIP becomes tyrosine-phosphorylated following stimulation of cells with insulin,
  • NCI Pathway Database BCR signaling pathway: SHIP (INPP5D) → B-cell antigen/BCR complex/Btk/LYN/SYK/BLNK/PLCgamma2 complex (BTK-PLCG2-SYK-CD79B-LYN-CD79A-BLNK) (modification, inhibits)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *