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NOX1 — PRKCA
Text-mined interactions from Literome
Fontayne et al., Biochemistry 2002
:
Taken together, these results suggest that
PKC alpha , beta II, delta, and zeta expressed in human neutrophils can individually phosphorylate p47(phox) and
induce both its translocation and
NADPH oxidase activation
Abdala-Valencia et al., J Immunol 2006
:
The anti-VCAM-1 stimulated phosphorylation of
PKCalpha ( Thr638 ) was
blocked by scavenging of H ( 2 ) O ( 2 ) and by inhibition of
NADPH oxidase
Thallas-Bonke et al., Diabetes 2008
(Diabetes Mellitus, Experimental...) :
In the context of these and previous findings by our group, we conclude that
activation of
NADPH oxidase via phosphorylation of
PKC-alpha is downstream of the AGE-receptor for AGE interaction in diabetic renal disease and may provide a novel therapeutic target for diabetic nephropathy
Hong et al., American journal of physiology. Renal physiology 2010
:
We concluded that flow stimulates net O ( 2 ) ( - ) production in thick ascending limbs via
PKC-alpha mediated
activation of
NADPH oxidase