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ALB — IGF1
Text-mined interactions from Literome
Ishida et al., Int J Mol Med 2004
:
The production of
albumin in osteoblastic cells was significantly enhanced in the
presence of PTH,
IGF-I , 17beta-estradiol or zinc sulfate
Lin et al., Zhongguo Zhong Yao Za Zhi 2005
(Bone Neoplasms...) :
Deer serum
albumin , with the molecular weight of 56.3 kDa, significantly
increased the proliferation rate of the osteoblast-like UMR-106 cell and
IGF-I secretion
Masumoto et al., Fukuoka Igaku Zasshi 1991
:
Conversely, glucagon stimulated the production of
IGF-I at concentrations over 10 ( -8 ) M, but
inhibited the production of
albumin at concentrations over 10 ( -10 ) M. Dexamethasone stimulated the production of IGF-I at concentrations over 10 ( -7 ) M, but had no significant effects on the production of albumin
Zvibel et al., J Cell Physiol 1995
(Carcinoma, Hepatocellular...) :
In HepG2 cells,
IGF II
increased albumin mRNA levels and resulted in a shift from clusters of cells positive to 100 % of the cells expressing immunohistochemically detectable albumin ... In FTO-2B cells,
IGF II
increased the expression of
albumin , CK19, and GGT, without accompanying changes in albumin and GGT mRNAs
Ballmer et al., J Clin Invest 1995
(Acidosis...) :
The effect on
albumin synthesis may be
mediated , at least in part, by a suppression of
insulin-like growth factor-I , free thyroxine and tri-iodothyronine
Gronowski et al., Endocrinology 1996
:
The activation of
insulin-like growth factor I and Spi 2.1 gene expression and the
inhibition of
albumin transcription also are not blocked by CHX, suggesting that these effects are primary consequences of GH-activated signal transduction pathways