Gene interactions and pathways from curated databases and text-mining

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CAT — TNF

Text-mined interactions from Literome

Naitoh et al., Cell Signal 2001 (Insulin Resistance) : Catalase completely inhibited GHA induced TNF-alpha release ; however, superoxide dismutase ( SOD ) had no effect
Chen et al., J Pharmacol Exp Ther 2003 : In contrast, Ad.N17Rac1 inhibited TNF-alpha induced NF-kappaB-driven HIV ( kappaB ) ( 4 ) -CAT and p288VCAM-Luc promoter activity, suggesting that N17Rac1 inhibits TNF-alpha induced VCAM-1, E-selectin, and ICAM-1 through suppressing NF-kappaB mediated transactivation
Campo et al., Life Sci 2004 (Carbon Tetrachloride Poisoning...) : Carbon tetrachloride produced a marked increase in serum alanine aminotransferase and aspartate aminotransferase activities, primed lipid peroxidation, enhanced plasma TNF-alpha levels, induced a severe depletion of reduced glutathione and catalase , and promoted neutrophil accumulation
Lecour et al., Cardiovasc Res 2005 (Myocardial Ischemia...) : TNF alpha-perfusion increased catalase activity in the ventricles ( 15.8+/-1.2 I.U./mg for controls vs. 19.9+/-1.1 I.U/mg for TNF alpha, p < 0.05 )
Xing et al., Chin Med J (Engl) 2005 (Hepatitis B, Chronic) : The activity of the CAT gene at these point mutations of HPRE could be inhibited by IFN-alpha/gamma and tumor necrosis factor (TNF)-alpha except for the point mutations at nt 1508 of HPRE which may escape the suppression role of IFN-alpha on HPRE
Basuroy et al., Am J Physiol Cell Physiol 2006 : The TNF-alpha response was inhibited by superoxide dismutase and catalase suggesting apoptosis is oxidative stress related
Jekabsone et al., Journal of neuroinflammation 2006 : Production of TNF-alpha and IL-1beta, measured after 24 hours of Abeta treatment, was also prevented by apocynin, catalase and EUKs, but the early release ( measured after 1 hour of Abeta treatment ) of TNF-alpha was insensitive to apocynin or catalase
Imrich et al., Toxicol Appl Pharmacol 2007 : N-Acetyl-l-cysteine ( 20 mM ), dimethyl thiourea ( 20 mM ) and catalase ( 5 microM ) significantly inhibited TNF release by primed AMs incubated with CAPs
Hu et al., J Ethnopharmacol 2008 (Drug-Induced Liver Injury) : Pretreatment with CGX significantly restored the reduction of catalase activity and glutathione ( GSH ) content, but not superoxide dismutase ( SOD ) activity, and it inhibited the CCl ( 4 ) -induced high expression of iNOS and TNF-alpha in hepatic tissue
Siwale et al., Journal of drug targeting 2009 (Disease Models, Animal...) : Microencapsulated ( MC ) catalase has been shown to inhibit H ( 2 ) O ( 2 ) and tumor necrosis factor (TNF) in vitro after endotoxin stimulation
Matsuda et al., J Biol Chem 2010 : ClC-3 expression induced ICl ( swell ) in ClC-3 null cells in the absence of swelling or TNF-alpha , and this effect was also blocked by catalase
Omary et al., AIDS 1991 : In SW620 and HT29 cells transfected with the HIV-1 long terminal repeat ( LTR ) linked to the chloramphenicol acetyl transferase (CAT) reporter gene, an intact HIV-1 enhancer element was required for stimulation of CAT activity by tumor necrosis factor alpha (TNF alpha) and phorbol ester
Latham et al., Cell Immunol 1990 : In this model system, endotoxin lipopolysaccharide (LPS) and tumor necrosis factor-alpha (TNF-alpha) are able to independently stimulate expression of LTR-CAT
Suzuki et al., Biochem Biophys Res Commun 1995 : Transient overexpression of catalase does not inhibit TNF- or PMA induced NF-kappa B activation ... Overexpression of catalase , however, did not block TNF- or PMA induced NF-kappa B activation
Nanes et al., Endocrinology 1994 : TNF alpha inhibited 1,25- ( OH ) 2D3 stimulated, but not basal, CAT activity
Flad et al., Arch Immunol Ther Exp (Warsz) 1995 (Leprosy, Lepromatous...) : Furthermore, M. kansasii with high intrinsic catalase induce less TNF-alpha than mycobacteria with low intrinsic catalase