Singh et al., J Clin Invest 1999
(Inflammation) :
In summary, IL-1 activated RhoA , which was physically associated with IL-1Rcd and necessary for activation of cytosolic nuclear signaling pathways
Lin et al., Rheumatol Int 2011
(Arthritis, Rheumatoid) :
RhoA inhibition either with a specific inhibitor or by siRNA transfection inhibited activation of NF-?B and secretion of TNFa and IL-1ß in PG-induced RA monocytes