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EGF — TWIST1

Text-mined interactions from Literome

Lo et al., Cancer Res 2007 (Breast Neoplasms...) : In search of a downstream mediator that may account for EGF induced EMT, we focused on transcription repressors of E-cadherin, TWIST, SLUG, and Snail and found that cancer cells express high levels of TWIST and that EGF enhances its expression ... EGF significantly increases TWIST transcripts and protein in EGFR expressing lines ... Chromatin immunoprecipitation assays further show that EGF induces binding of nuclear STAT3 to the TWIST promoter
Bridges et al., Am J Pathol 2009 (Pulmonary Fibrosis) : Twist1 was induced by the profibrotic growth factors ( GFs ) basic fibroblast growth factor, platelet derived growth factor, and epidermal growth factor in primary rat lung fibroblasts ( RLFs )
Pallier et al., PloS one 2012 (Adenocarcinoma...) : Moreover a decrease of EGFR pathway stimulation through EGF retrieval or an inhibition of TWIST1 expression by small RNA technology reversed the phenomenon